Therefore, impaired liver function is unlikely to result in lorazepam accumulation to an extent causing adverse reactions.

You may also have seizures or withdrawal symptoms when you stop using Ativan. Lorazepam's relatively short serum half-life, its confinement mainly to the vascular space, and its inactive metabolite results in interdose withdrawal phenomena and next-dose cravings. Full lists of Lorazepam side effects:For lists of lorazepam side effects, refer to the manufacturers' data sheets. Lorazepam-glucuronide is more water-soluble than its precursor and, therefore, gets more widely distributed in the body, leading to a longer half-life than lorazepam. 5 mg, 1 mg, or 2 mg lorazepam, with some differences between countries. 9%), weakness (4. Less serious Ativan side effects may include:* drowsiness, dizziness, tiredness; * blurred vision; * sleep problems (insomnia); * muscle weakness, lack of balance or coordination; * amnesia or forgetfulness, trouble concentrating; * nausea, vomiting, constipation; * appetite changes; or * skin rash. edit Other useSee also: Nonmedical benzodiazepine drug useLorazepam is also used for other purposes. Otherwise, management is by observation, including of vital signs, support and, only if necessary, considering the hazards of doing so, giving intravenous flumazenil. Like oxazepam, it does not require hepatic oxidation, but only hepatic glucuronidation into lorazepam-glucuronide.